NOT KNOWN DETAILS ABOUT MAKATUSSIN SYROP

desvenlafaxine will increase the amount or influence of codeine by impacting hepatic enzyme CYP2D6 metabolism. Use Warning/Watch. Desvenlafaxine inhibits CYP2D6; with greater desvenlafaxine doses (ie, four hundred mg) decrease the CYP2D6 substrate dose by nearly 50%; no dosage adjustment needed with desvenlafaxine doses seven consecutive days immed